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SC Proven Reference Publications

The following is a select list of peer-reviewed publications referencing the use of StemCells SC Proven products. These publications can also be accessed online at PubMed.gov.

GS1-R

Tong C, et al. (2010) Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature doi:10.1038/nature09368.

Leitch H, et al. (2010) Embryonic germ cells from mice and rats exhibit properties consistent with a pluripotent ground state. Development 137(14): 1-9.

Smith A, (2009) Design principles of pluripotency. EMBO Molecular Medicine 1(5):251-4.

Buehr M, et al. (2008) Capture of authentic embryonic stem cells from rat blastocysts. Cell 135(7):1287-98.

Li P, et al. (2008) Germline competent embryonic stem cells derived from rat blastocysts. Cell 135(7):1299-310.

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GS2-M

Hanna J, et al. (2010) Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ES cells. PNAS 107(20): 9222-7.

Silva J, et al. (2009) Nanog is the Gateway to the Pluripotent Ground State. Cell 138 (4): 722-737.

Silva J, et al. (2008) Promotion of Reprogramming to Ground State Pluripotency by Signal Inhibition. PLoS Biol. 6: e253.

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iSTEM®

Ying QL, et al. (2008) The ground state of embryonic stem cell self-renewal. Nature 453:519-523.

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NDiff® N2 and NDiff® N2-AF

Bottenstein JE, Cell Culture in the Neurosciences. Plenum Press (1985) New York and London.

Ying QL, Smith AG, Defined conditions for neural commitment and differentiation. Methods Enzymol. (2003) 365:327-341.

Ying QL, et al., Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nature Biotechnology (2003) 21:183-186.

Nichols J, Ying QL, Derivation and propagation of embryonic stem cells in serum- and feeder-free culture. Methods Mol Biol. (2006) 329:91-98.

Conti L, et al., Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol. (2005) 3(9):e283.

Pollard SM, et al., Adherent neural stem (NS) cells from fetal and adult forebrain. Cereb. Cortex (2006) 16 Suppl 1:112-20.

Conti L, et al., Neural stem cell systems: diversities and properties after transplantation in animal models of diseases. Brain Pathol. (2006) 16(2):143-154.

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NDiff® N27 and NDiff® N27-AF

Ying QL, Smith AG, Defined conditions for neural commitment and differentiation. Methods Enzymol. (2008) 365:327-341.

Ying QL, et al., Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat. Biotech. (2003) 21:183-186.

Conti L, et al., Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biol. (2005) 3(9):e283.

Pollard SM, et al., Adherent neural stem (NS) cells from fetal and adult forebrain. Cereb. Cortex (2006) 16 Suppl 1:112-20.

Conti L, et al., Neural stem cell systems: diversities and properties after transplantation in animal models of diseases. Brain Pathol. (2006) 16(2):143-154.

Nichols J, Ying QL, Derivation and propagation of embryonic stem cells in serum- and feeder-free culture. Methods Mol. Biol. (2006) 329:91-98.

Liu Y, et al., A novel chemical-defined medium with bFGF and N2B27 supplements supports undifferentiated growth in human embryonic stem cells. BBRC (2006) 346:131-139.

Yao S, et al., Long-term self-renewal and directed differentiation of human embryonic stem cells in chemically defined conditions. PNAS (2006) 103(18):6907–6912.

Hanna J, et al., Human embryonic stem cells with biological and epigenetic characteristics similar to those of mouse ES cells. PNAS (2010)107(20):9222-7.

Yu J, et al., Efficient Feeder-Free Episomal Reprogramming with Small Molecules. PLoS ONE (2011) 6(3):e17557.

Tsutsui H, et al., An optimized small molecule inhibitor cocktail supports long-term maintenance of human embryonic stem cells. Nat. Commun. (2011) 2:167.

Brewer G, et al., Optimized Survival of Hippocampal Neurons in B27-Supplemented Neurobasal™, a New Serum-free Medium Combination. J. Neurosci. Res. (1993) 35:567–57.

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NDiff® N2B27

Morrison G, et al. (2008) Anterior definitive endoderm from ESCs reveals a role for FGF signaling. Cell Stem Cell 3:402-415.

Ying QL, et al. (2003) Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nature Biotechnology 21:183-186.

Ying QL, et al. (2003) BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 115:281-292.

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RHB-A® and RHB-Basal®

Fernandes et al. (2010) Hypoxia enhances proliferation of mouse embryonic stem cell-derived neural stem cells. Biotechnology and Bioengineering 106: 260–270.

Fernandes, T.G., et al. (2010) Different stages of pluripotency determine distinct patterns of proliferation, metabolism, and lineage commitment of embryonic stem cells under hypoxia. Stem Cell Research doi:10.1016/j.scr.2010.04.003.

Fernandes et al. (2010) Three-dimensional cell culture microarray for high-throughput studies of stem cell fate. Biotechnology and Bioengineering 106: 106-118.

Hansen, et al. (2010) Neurogenic radial glia in the outer subventricular zone of human neocortex. Nature doi:10.1038/nature08845.

Abranches E, et al. (2009) Neural differentiation of embryonic stem cells in vitro: A road map to neurogenesis in the embryo. PLoS ONE 4(7): e6286

Pollard SM, et al. (2009) Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens. Cell Stem Cell 4:568-580.

Sun Y, et al. (2008) Long-term tripotent differentiation capacity of human neural stem (NS) cells in adherent culture. Molecular and Cellular Neuroscience 38:245-258.

Pollard SM, et al. (2008) Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation. Molecular and Cellular Neuroscience 38:393:403.

Diogo MM, et al. (2008) Optimization and integration of expansion and neural commitment of mouse embryonic stem cells. Biotechnology and Applied Biochemistry 49:105-112.

Pollard SM, et al. (2006) Adherent Neural Stem (NS) cells from fetal and adult forebrain. Cerebral Cortex 16:112-120.

Conti L, et al. (2005) Niche-Independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biology 3(9):e283.

Ying QL, et al. (2003) Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nature Biotechnology 21:183-186.

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STEM24

Alterman LA, et al. Characterization of the murine heat-stable antigen: An hematolymphoid differentiation antigen defined by the J11d. M1/69 and B2A2 antibodies. Eur. J. Immunol. (1990) 20:1597-1602

Allman DM, et al. Peripheral B cell maturation. I. Immature peripheral B cells in adults are heat-stable antigen hi and exhibit unique signaling characteristics. J. Immunol. (1992) 149:2533-2540

Nielsen PJ, et al. Altered erythrocytes and a leaky block in B-cell development in CD24/HAS-deficient mice. Blood (1997) 89: 1058-1067

Baumann P, et al. CD24 expression causes the acquisition of multiple cellular properties associated with tumor growth and metastasis. Cancer Res. (2005) 65:10783-10793

Pruszak J, et al. CD15, CD24, and CD29 Define a surface biomarker code for neural lineage differentiation of stem cells. Stem Cells (2009) 27:2928-2940

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STEM101

Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074

Guzman R, et al. Long-term monitoring of transplanted human neural stem cells in developmental and pathological contexts with MRI . PNAS (2007) 104: 10211-10216

Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319

Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5: e12272

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STEM121

Kelly S, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. PNAS (2004) 101:11839 11844.

Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074

Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319

Kallur T, et al. Human Fetal Cortical and Striatal Neural Stem Cells Generate Region-Specific Neurons in vitro and Differentiate Extensively to Neurons After Intrastriatal Transplantation in Neonatal Rats. J Neurosci Res. (2006) 84:1630-1644

Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5: e12272

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STEM123

Tamaki SJ, et al. Neuroprotection of Host Cells by Human Central Nervous System Stem Cells in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis. Cell Stem Cell (2009) 5:310-319

Salazar DL, et al. Human Neural Stem Cells Differentiate and Promote Locomotor Recovery in an Early Chronic Spinal Cord Injury NOD-scid Mouse Model. PLoS ONE (2010) 5:e12272&nd

Cummings BJ, et al. Human neural stem cells differentiate and promote locomotor recovery in spinal cord-injured mice. PNAS (2005) 102: 14069-14074

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STEM133

Yin, A. H. et al. AC133, a novel marker for human hematopoietic stem and progenitor cells. Blood (1997) 90:5002–5012

Buhring, H. J. et al. Expression of novel surface antigens on early hematopoietic cells. Ann NY Acad Sci. (1999) 872:25–39

Uchida N, et al. Direct Isolation of human central nervous system stem cells. PNAS (2000) 97:14720-14725

Peichev, M. et al. Expression of VEGFR-2 and AC133 by circulating human CD34(+) cells identifies a population of functional endothelial precursors. Blood (2000) 95:952–958

Singh SK, et al. Identification of human brain tumour initiating cells. Nature (2004) 432:396-401

Weigmann A, et al. Prominin, a novel microvilli-specific polytopic membrane protein of the apical surface of epithelial cells, is targeted to plasmalemmal protrusions of non-epithelial cells. PNAS (1997) 94:12425-12430

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STEMmES

Ying QL, et al., The ground state of embryonic stem cell self-renewal. Nature (2008) 453(7194):519-23
 
Buehr M, et al., Capture of Authentic Embryonic Stem Cells from Rat Blastocysts. Cell (2008) 135(7):1287-98

Li P, et al., Germline Competent Embryonic Stem Cells Derived from Rat Blastocysts. Cell (2008) 135(7):1299-310
 
Wray J, et al., The ground state of pluripotency. Biochem Soc Trans. (2010) 38(4):1027-325

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STEMmENSand STEMmFNS

Conti L, et al., Niche-independent symmetrical self-renewal of a mammalian tissue stem cell. PLoS Biology (2005) 3(9):e283
 
Pollard SM, et al., Adherent Neural Stem (NS) cells from fetal and adult forebrain. Cerebral Cortex (2006) 16:112-120
 
Pollard SM, et al., Fibroblast growth factor induces a neural stem cell phenotype in foetal forebrain progenitors and during embryonic stem cell differentiation. Molecular and Cellular Neuroscience (2008) 38:393:403

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  • *TERMS & CONDITIONS
  • 10% off your next SC Proven order.
  • Limit of one discount per publication.
  • Not applicable with any other discount or offer.
  • Only applicable to peer-reviewed journals.
  • Article must have been published within the last 2 years.
  • StemCells, Inc., Stem Cell Sciences or a SC Proven product name must be mentioned in the methods section of the article.
  • Person submitting must be an author of the article.
  • StemCells, Inc. reserves the right to change or discontinue this program at any time.

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Mouse E14 ES cells differentiated into Tuj 1 positive neurons in monoculture with NDiff® N2 supplemented media.

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