Published and Presented Studies Involving the Company's Technology

2004

Kelly S, Bliss TM, Shah AK, Sun GH, Ma M, Foo WC, Masel J, Yenari MA, Weissman IL, Uchida N, Palmer T, Steinberg GK. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11839-44.

Baiker A, Fabel K, Cozzio A, Zerboni L, Fabel K, Sommer M, Uchida N, He D, Weissman I, Arvin AM. Varicella-zoster virus infection of human neural cells in vivo. Proc Natl Acad Sci U S A. 2004 Jul 20;101(29):10792-7.

Cummings B, Uchida N, Tamki S, Sears-Kraxberger I, Anderson A, Behavioral improvement, differentiation, and immuno-electron microscopy of human central nervous system stem cells in spinal cord injured NOD-Scid and NOD-Scid/Shiverer mice. SFN abs. Oct 24, 2004.

Uchida N, Tamaki S, Anderson A, Cummings B, Capela A, Dohse M, Eckert K. He D, Jacobs Y, Tushinski R , Tsukamoto A. Biology of human central nervous system stem cells. SFN abs. Oct 27, 2004.

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2003

Austin T, Lagasse A. Hepatic regeneration from hematopoietic stem cells Mod (120) p131 2003

Basu, S.B., Belichenko, P.V., Uchida, N., Tamaki, S., Eckert, K., Udani, V., Tsukamoto, A., Mobley, W.C. Brain transplantation of human neural stem cells in mouse model of Batten's disease. SFN abs. Nov 10, 2003.

Cummings, B.J., Uchida, N., Salazar, D.L., Tamaki, S., Dohse, M., Tushinski, R., Tsukamoto, A.S., Anderson. A.J. Transplantation of human central nervous system stem cells into a NOD - SCID mouse model of spinal cord contusion injury. SFN abs. Nov 10, 2003.

Tamaki S., Capela A, Dohse M, Eckert K, He D, Tushinski R, Tsukamoto A., Basu S, Belichenko P, Mobley W, Cummings B, Anderson A, Uchida N. Use of human central nervous system stem cells for neurodegenerative disease and CNS injury. SFN abs. Nov. 11, 2003.

Kelly, S., Bliss, T.M., Shah, A.K., Sun, G., Puja, K., Ma, M., Foo, W., Masel, J., Shallert, T., Yenari, M.A., Uchida, N., Palmer, T., Steinberg, G.K. Human fetal CNS stem cell neurospheres survive, migrate and differentiate following transplantation into ischemic rat cerebral cortex. SFN abs. Nov. 12, 2003.

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2002

Tamaki S, Eckert, K, He, D. Sutton,R., Doshe, M. Jain G., Tushinski, R., Michael Reitsma, Harris, B., Tsukamoto, A., Gage, F, Irving Weissman, I., Uchida, N. Engraftment of Sorted/Expanded Human Central Nervous System Stem Cells From Fetal Brain. Journal of Neuroscience Research. 2002; 69:976-986.

Kelly, S., Bliss, T., Sun, G.H. Kohli,P., Ma,M. Foo,W. Price, R., Schallert,T., Yenar.M.i, Uchida, N, Palmer, T., Steinberg, G. Human Fetal CNS Stem Cell Neurosphere Transplant for Rat Cortical Stroke: Functional Outcome, Cell Survival, Migration, and Differentiation. SFN abs. Nov 6, 2002.

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2001

Lagasse E, Shizuru JA, Uchida N, Tsukamoto A, Weissman IL. Toward regenerative medicine. Immunity. 2001 Apr;14(4):425-36.

Uchida, N. Similarity and differences between the haemopoietic and brain stem cell system. Symp Soc Exp Biol. 2001;(53):21-8.

Tamaki, S., Eckert, K., He, D., Dohse, M., Jain, G., Buck, D.W., Tsukamoto, A.S., Gage, G.H., Weissman, L.L., Uchida, N. Human Specific Monoclonal Antibodies Reveal Engraftment, Proliferation, and Differentiation of Transplanted Human CNS-SC In NOD-SCID Recipient Mice. SFN abs. Nov 13, 2001

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2000

Uchida N, Buck DW, He D, Reitsma MJ, Masek M, Phan TV, Tsukamoto AS, Gage FH, Weissman IL. Direct isolation of human central nervous system stem cells. Proc Natl Acad Sci U S A. 2000 Dec 19;97(26):14720-14725.

Lagasse E, Connors H, Al-Dhalimy M, Reitsma M, Dohse M, Osborne L, Wang X, Finegold M, Weissman IL, Grompe M. Purified hematopoietic stem cells can differentiate into hepatocytes in vivo. Nat Med. 2000 (11):1229-34.

Uchida, N., He, D., Buck, D., Reitsma, D., Masek, T, Phan,T., Tsukamoto, A.S., Weissman, I., ., Gage, R. Reisolation of Continuously Regenerating Human Neural Stem/Progenitor AC133+ Cells From Transplanted Mouse Brain. SFN abs. Nov 6, 2000.

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1999

Fricker RA, Carpenter MK, Winkler C, Greco C, Gates MA, Bjorklund A.Site-Specific Migration and Neuronal Differentiation of Human Neural Progenitor Cells after Transplantation in the Adult Rat Brain. The Journal of Neuroscience, 1999, 19(14):5990-6005

Carpenter MK, Cui X, Hu ZY, Jackson J, Sherman S, Seiger A, Wahlberg L In vitro expansion of a multipotent population of human neural progenitor cells. Experimental Neurology,1999, 158, 265-278

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